Official dog supplement description: “Grizzly Salmon Oil contains extremely healthy long-chain Omega 3 fatty acids and natural anti-oxidants. Grizzly Salmon Oil is extracted from wild caught Alaskan Salmon, never farmed. Grizzly Pet Products owns and operates 3 processing plants in the state of Alaska and uses only clean naturally raised Salmon. Grizzly Salmon Oil is rich in EPA and DHA fatty acids. EPA assists the body to supplement the skin and coat, and bolster the immune system.”[tabs][tab title =”Overview”]Grizzly Salmon Oil supplies a daily supplement rich in EPA and DHA – the right omega-3 fatty acids. The recommended daily dose of Grizzly Salmon Oil yields approximately 500 to 2500 milligrams of these important fatty acids, depending on your pet’s weight.
When given to your dog as directed according to weight, Grizzly Salmon Oil delivers approximately 50-300 milligrams of linoleic acid, the essential omega-6 fatty acid. Other omega-6 fatty acids are present in only very small amounts.[/tab]
[tab title =”Ingredients”]Natural Wild Alaskan Salmon Oil[/tab]
[tab title =”Analysis”]Crude fat: 99.9% (min.)
Moisture: 0.1% (max.)
Omega-3 Fatty Acids*: 29.0% (min.)
DHA (Docosahexaenoic Acid)*: 12.0% (min.)
EPA (Eicosapentaenoic Acid)*: 9.0% (min.)
Omega-6 Fatty Acids*: 3.0% (min.)
*Not recognized as an essential nutrient by the AAFCO Dog Food Nutrient profile. [/tab] [tab title=”Uses”]Add daily to your dog’s food according to the weight chart below. If one pump stroke equals approx. 0.12 fl oz / 3.5 ml, then for best results, use regularly on a long-term basis as recommended below:
Up. to 12.5 lbs. – 1/2 pump stroke
Up to 12.5 – 25 lbs. – 1 pump stroke
Up to 25 – 50 lbs. – 2 pump strokes
Up to 50 – 75 lbs. – 3 pump strokes
Over 75 lbs. – 4 pump strokes[/tab] [tab title =”Side Effects”]No reported side effects as of this writing; see detailed breakdown below.[/tab][/tabs]
Grizzly Salmon Oil
Grizzly Salmon Oil is a supplement produced specifically for dogs and cats using an anaerobic in-line extraction process in a dedicated salmon production plant. This supplement promotes coat quality, immune health, and heart health for dogs.
Recent clinical studies, as outlined below, support fish oil supplementation for a very wide variety of aspects of canine well-being. Choosing a high-grade supplement, prepared freshly from wild-caught fish and free of rancidity, is likely to be a wise choice.
Breakdown of Grizzly Salmon Oil review
Glizzly Salmon Oil dog supplement is a source of 100% pure salmon oil that comes from wild Alaskan Salmon. It’s considered to be a good source of omega-3 and omega-6 fatty acids.
While omega-6 polyunsaturated fatty acids (PUFAs) are found in a large variety of foods, omega-3 are mostly found in the highest concentrations in deep-water oily fish, such as mackerel, tuna, and salmon. However, like all fats, exposure to light, heat, and even air can cause rancidity or spoiling, thus quality preparation matters.
Although precise numbers vary, basing their decision on some studies, ISSFAL suggests  that for people, a dietary ratio of one part omega-3 to five parts omega-6 (1:5), or roughly 500mg a day of omega-3 is the optimal amount. The daily recommended dose of Grizzly Salmon Oil supplement is 500mg to 2500 mg, depending upon your dog’s weight.
Using a hand pump, the oil is simply pumped onto your dog’s food. Research suggests  that it takes from four to six weeks for effects to be noticed.
Why should you give this supplement to a healthy dog?
As outlined below, supplementation with omega-3 offers clear benefits for completely healthy dogs, too. The benefits include improved skin, coat, eyes, immune system, heart, and nervous system. Of particular interest, canine athletes in the annual Alaskan Iditerod Race are typically fed salmon both before and during the race for the best performance.
Are there any side effects?
At the time of this writing, there are no reported side effects of Grizzly Salmon Oil supplement for dogs. Your pet may require a few days to adjust to the change in dietary habits. Initial supplementation with omega-3 causes diarrhea in some cases, therefore, the supplement should be introduced gradually and with close supervision. As with other supplements, it’s always wise to consult your veterinarian.
Summary of supplement’s effects
Perhaps most important for the dog owner to know is that, at present, there seems to be a few adverse health effects from fish oil supplementation that are attributed only to over-consumption of essential fatty acids.
However, while research in canines is not yet wholly conclusive, a significant amount of scientific evidence suggests that fish oil supplements – including Grizzly Salmon Oil – are very beneficial for the dog’s healthy lifestyle. That being said, successful supplementation does require proven quality product as a source of essential fatty acids that is free from oxidation due to mishandling. It’s safe to say that Grizzly Salmon Oil, being a 100% pure salmon oil, qualifies as a safe supplement for dogs.
PUFAs for dog health
The dietary benefits of polyunsaturated fatty acids (PUFAs) have been known for nearly 100 years. Since that time, an increasing number of studies on PUFAs in animals and humans have led to an understanding of two important major categories: omega-3 and omega-6 fatty acids. Both are considered essential dietary requirements, meaning that the dog’s body cannot produce them for itself.
Unlike other dietary fats, PUFAs are not used for energy production and/or storage, but are used as critical structural components. Omega-3 fats are an important component of most cell membranes in mammals. Omega-3 and omega-6 PUFA’s are also important in biosynthesis of eicosanoids – compounds which function in many complex ways over the entire canine body: brain, nervous system, retina, skin, stomach, cardiovascular system, and even in muscles and joints.
The most important omega-3 PUFA’s are the well-known EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). Linoleic acid (LA) is an important omega-6 PUFA which is also found in fish oils. Because the biochemical pathways using omega-3 and omega-6 are the same, the dietary ratio of these fats is somewhat important for optimal physiological function, that way placing the proper fat into its optimal place in the canine cellular membranes.
EPA and DHA appear to function uniquely and separately: EPA regulates cellular activity, cardiovascular function, and may have a preventative role in both strokes and cancer. In contrast, DHA is more important for both the nervous system (brain) and the eyes (retina).
There is a considerable growing body of clinical research in dogs that is focused on a variety of approaches to investigating just how omega-3 PUFAs function in healthy and ill canines. This includes work examining EPA and DHA both together and separately in order to understand more precisely the physiological role of these essential fatty acids.
Let’s summarize a few of such studies.
Effects of the omega-3 PUFAs are presently contradictory with respect to canine blood coagulation [3, 4], which suggests the need for further analysis. Evidence of improved gait, movement, and daily activity in arthritic canines have been reported [5, 6]. Decreased dosage of carprofen (NSAID) was also reported upon omega-3 supplementation for osteoarthritic canines . Omega-3 also seem to have beneficial effects on canine atopic dermatitis and itchy skin .
EPA and DHA have been used in cancer treatment and they improve the efficacy of chemotherapy . Indeed, supplementation with omega-3 PUFAs has been shown to inhibit the growth of tumors, as well as increasing survival time and disease-free intervals for dogs undergoing chemotherapy with doxorubicin , while another study on dogs with lymphoma says more research is required to know how fatty acids affect dogs .
Precisely how omega-3 improves dog’s well-being – even during treatment of cancer – is not yet known, but the fact remains that it does have a positive effect.
Studies with humans indicate that omega-3 decrease the risk of sudden cardiac death (SCD) , and related research in canines reveals that DHA (but not EPA) reduces the risk of atrial fibrillation in dogs . Omega-3 PUFAs are cardio-protective even for dogs that had previously experienced heart attacks .
In addition, omega-3 assist in lowering serum triglycerides and adipokines in dogs, which is of potential importance with respect to diabetes prevention and treatment . Finally, DHA increases a variety of mental abilities in puppies after weaning, as well as supporting retinal functions and improving immune system response .
While these data are not by any means final, it is evident that there are considerable health benefits for dogs that regularly consume omega-3 PUFAs either through diet or supplementation. Many veterinarians and scientists continue to push for further research, such as canine arthritis treatment through diet and supplementation [17, 18]. Some contradictory findings  in dogs with respect to the cardio-protective role of omega-3 also indicate a need for additional studies .
- ISSFAL: Report of the sub-committee on recommendations of intake of polyunsaturated fatty acids in healthy adults. June 2004. [pdf]
- Mueller, R. et al. Effect of omega-3 fatty acids on canine atopic dermatitis. J Small Anim Pract. 2004 Jun;45(6):293-7. [study]
- Hesta, M et al. Biological effects of short-term salmon oil administration, using distinct salmon oil sources in healthy dogs. J Small Anim Pract. 2012 Dec;53(12):699-704. doi: 10.1111/j.1748-5827.2012.12000
- Lenox, C et al. Potential adverse effects of omega-3 Fatty acids in dogs and cats. J Vet Intern Med. 2013 Mar-Apr;27(2):217-26. doi: 10.1111/jvim.12033
- Rialland, P et al. Effect of a diet enriched with green-lipped mussel on pain behavior and functioning in dogs with clinical osteoarthritis. Can J Vet Res. 2013 Jan;77(1):66-74. [study]
- Moreau, M et al. Effects of feeding a high omega-3 fatty acids diet in dogs with naturally occurring osteoarthritis. J Anim Physiol Anim Nutr (Berl). 2012 Jul 14. doi: 10.1111/j.14390396.2012.01325
- Fritsch, D et al. A multicenter study of the effect of dietary supplementation with fish oil omega-3 fatty acids on carprofen dosage in dogs with osteoarthritis. J Am Vet Med Assoc. 2010 Mar 1;236(5):535-9. doi: 10.2460/javma.236.5.535
- Mueller, R. et al. Effect of omega-3 fatty acids on canine atopic dermatitis. J Small Anim Pract. 2004 Jun;45(6):293-7. [study]
- Biondo, P et al. The potential for treatment with dietary long-chain polyunsaturated n-3 fatty acids during chemotherapy. J Nutr Biochem. 2008 Dec;19(12):787-96. doi: 10.1016/j.jnutbio.2008.02.003
- Ogilvie, G et al. Effect of fish oil, arginine, and doxorubicin chemotherapy on remission and survival time for dogs with lymphoma: a double-blind, randomized placebo-controlled study. Cancer. 2000 Apr 15;88(8):1916-28. [study]
- Seltin, K et al. Evaluation of the effects of dietary n-3 fatty acid supplementation on the pharmacokinetics of doxorubicin in dogs with lymphoma. Am J Vet Res. 2006 Jan;67(1):145-51. [study]
- Christensen, J. et al. n-3 fatty acids and the risk of sudden cardiac death. Emphasis on heart rate variability. Dan Med Bull. 2003 Nov;50(4):347-67. [study]
- Ramadeen, A. et al. Docosahexaenoic acid, but not eicosapentaenoic acid, supplementation reduces vulnerability to atrial fibrillation. Circ Arrhythm Electrophysiol. 2012 Oct;5(5):978-83. doi: 10.1161/CIRCEP.112.971515
- Billman, G. Effect of dietary omega-3 polyunsaturated Fatty acids on heart rate and heart rate variability in animals susceptible or resistant to ventricular fibrillation. Front Physiol. 2012 Mar 27;3:71. doi: 10.3389/fphys.2012.00071
- Mazaki-Tovi, M. Effect of omega-3 polyunsaturated fatty acids and body condition on serum concentrations of adipokines in healthy dogs. Am J Vet Res. 2012 Aug;73(8):1273-81. doi: 10.2460/ajvr.73.8.1273
- J. Zicker, S et al. Evaluation of cognitive learning, memory, psychomotor, immunologic, and retinal functions in healthy puppies fed foods fortified with docosahexaenoic acid-rich fish oil from 8 to 52 weeks of age. J Am Vet Med Assoc. 2012 Sep 1;241(5):583-94. doi: 10.2460/javma.241.5.583
- Perea, S. Nutritional management of osteoarthritis. Compend Contin Educ Vet. 2012 May;34(5):E4. [study]
- Vandeweerd, J et al. Systematic review of efficacy of nutraceuticals to alleviate clinical signs of osteoarthritis. J Vet Intern Med. 2012 May-Jun;26(3):448-56. doi: 10.1111/j.1939-1676.2012.00901.x
- Billman, G et al. Dietary omega-3 fatty acids and susceptibility to ventricular fibrillation: lack of protection and a proarrhythmic effect. Circ Arrhythm Electrophysiol. 2012 Jun 1;5(3):553-60. doi: 10.1161/CIRCEP.111.966739
- Freeman, L. Beneficial effects of omega-3 fatty acids in cardiovascular disease. J Small Anim Pract. 2010 Sep;51(9):462-70. doi: 10.1111/j.1748-5827.2010.00968.x
Disclaimer: The purported effects of the supplements or ingredients discussed in this article may, or may not, have been subject to rigorous scientific investigation. This article is an introductory document for educational purposes only which is not intended to be a scientific review either endorsing or refuting the claimed effects of the supplements or ingredients. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet. The supplement has not been tested or tried by the author(s) of the content/review, and are not endorsed or recommended in any way.