Deramaxx for Dogs - Dog Pain Medication ReviewVets run into this question often, “what can I give my dog for pain?Deramaxx for dogs is a popular, oft-recommended dog pain medication.

With age, dogs will begin to suffer from serious pain issues, usually due to canine arthritis and joint problems.

Young dogs may also experience uncomfortable pain on occasion, mostly post-surgery.

It’s always upsetting for owners to see their pets ache, but are painkillers for dogs the best solution?

Fortunately, there has been a lot of research done using NSAIDs with dogs.

Deramaxx for dogs is one of the most well-known non-steroidal pet pain medications alongside Rimadyl and Metacam.

In this article, we’ll go through Deramaxx review using evidence-based approach to decide how effective and safe this dog anti inflammatory really is.

What is Deramaxx for Dogs?

In order to know whether pain medication is right for your pet, it’s important to understand how dog pain medicine works.

Deramaxx is a trade name of this anti-inflammatory for dogs.

The legal term for this dog pain medication is Deracoxib. It belongs to a group of pain drugs called NSAIDs (non-steroidal anti-inflammatory drugs).

NSAIDs are non-narcotic and since the 1950s they have been used to treat pain and inflammation [1].

Let’s quickly get the scientific terminology out of the way and move onto the Deramaxx review.

In short, there are different types of NSAIDs for dogs, but they fall into two main categories:

  • COX-1 inhibitors
  • COX-2 inhibitors

These categories are based on the type of receptor that the drug mostly acts on.

Once an NSAID for dogs has inhibited the relevant COX receptors, which are found in different parts of the body, it helps to repress a series of reactions that lead to pain and inflammation, and therefore relieve their associated unpleasantness and discomfort.

The result of this inhibition is what causes the pain relieving effects of NSAIDs for dogs.

Deramaxx falls into a group called the coxib class of NSAIDs as it acts mainly on COX-2 receptors.

Several studies have reported that this type of NSAID for dogs has fewer unwanted side effects than those acting mainly on COX-1 receptors [2].

Deramaxx is mostly metabolized in the liver and then excreted in the dog’s feces.

The medication comes in the form of beef flavored chewable tablets produced by Elanco for use in dogs, and should not be used in cats.

Deramaxx for dogs tablets are available in different sizes to help ensure your pet receives an accurate dose, which is important for avoiding side effects.

The product was licensed in 2002 by the FDA, which regulates these types of medications and helps to ensure they are safe for pets.

What is Deramaxx Used to Treat?

Deramaxx for Dogs - Painkillers for DogsDeramaxx is used primarily to treat pain and inflammation in dogs, and has been shown to work well [3, 4].

This NSAID can be used either after orthopedic or dental surgery in dogs to improve how comfortable your pet feels, or in dogs that suffer from canine osteoarthritis and joint pain [5, 6, 7].

In canines with degenerative conditions such as osteoarthritis, Deramaxx provides relief from the pain but does not change the course of the damage that the condition causes.

The aim of using Deramaxx for dogs is to improve their quality of life by helping to ensure that pets suffer from as little pain as possible and can therefore lead an active and happy life.

Although less common, it has also been successfully used in the treatment of different types of canine cancers [8, 9, 10].

The product will often be combined with other dog cancer drugs to help maximize an animal’s chance of recovery [11, 12, 13, 14], and ensure pain relief [15, 16]. However, this is not what Deramaxx has been licensed for.

How Should Deramaxx be Used?

You should only give Deramaxx for dogs if a licensed vet has prescribed it.

Dosage. Deramaxx is usually given once a day and the dose recommended by your vet should be followed carefully.

Always use the appropriate sized tablets to ensure a correct dosage. This dose may vary depending on why your pet was prescribed this anti-inflammatory.

Timing. It’s best to discuss times of administration of this dog pain medicine with your vet.

Even though sources claim that it is most effective when given after your pet has been fed regular dog food, we were unable to locate any proof of this.

In fact, there’s loose evidence to the contrary.

Studies using a different brand of painkillers for dogs, Onsior, has shown that the bioavailability was 26% lower among dogs that were fed when compared to those that took the NSAID on an empty stomach [17, 18].

Combining. Care should be taken with Deramaxx for dogs that are taking any other medications.

Drugs which should not be given at the same time as Deramaxx include other NSAIDs and corticosteroids.

If your veterinarian prescribes it as a treatment, be sure to tell them if you are giving your dog any other medication.

In cases where Deramaxx is used to treat canine osteoarthritis, it should be combined with a healthy lifestyle to provide maximum benefit [19, 20].

Is Deramaxx Effective and Safe for Dogs?

Deramaxx for Dogs - Anti inflammatory for Dogs

Deramaxx has been in rotation since 2002, and this NSAID for dogs is now used in many practices on a regular basis.

A huge body of research is showing that Deramaxx for dogs is safe and effective [3-16, 21, 2223, 24].

Some smaller studies have shown either no effects at all on certain conditions (e.g. canine splenic hemangiosarcoma) in dogs and cats [25, 26], or minor side effects like vomiting and diarrhea in dogs [27].

With that being said, it’s important to note that most of these studies above were structured with healthy dogs. Further research is still required where dogs with different health issues are tested for the use of Deracoxib.

When Should Deramaxx be Avoided?

As with other NSAIDs, the use of Deramaxx should be avoided in dogs that are suffering from any liver or kidney problems [12, 21, 22].

NSAIDs for dogs can put a lot of extra strain on canine’s organs and may cause a worsening of the existing condition.

Deramaxx should be used with care or even avoided in dogs that have a known history of sensitivity to other NSAIDs, as they are likely to suffer from similar unwanted reactions.

To date, there are no studies demonstrating the safety of Deramaxx in pregnant or nursing dogs, so it should not be used to treat them.

Any Deramaxx Side Effects in Dogs?

Deramaxx Side Effects - Pain Killers for DogsLike all NSAIDs, there are some Deramaxx side effects that are minor, and they are commonly dose-related [21, 22, 25].

In general, most dogs will not experience any side effects from Deramaxx as noted above on the research of its efficacy and safety.

The side effects that you are most likely to see if your dog is affected are on the whole related to digestion, such as vomiting and diarrhea or reduced appetite [28].

Some of the other side effects Deramaxx can potentially cause but we’re yet to see any evidence of this are:

  • Other digestive issues, such as bloody feces, stomach ache and ulcers
  • Behavioral changes (alteration in activity, aggression)
  • Jaundice (a change in color of gums from pink to yellowish)
  • Loss of coordination and seizures
  • Skin problems (itchiness, redness or scabs)
  • Weight loss

If you are giving your dog Deramaxx and you notice that your canine is suffering from any of the above effects, then you should stop giving the drug immediately and call your vet.

Signs of Toxicity of Deramaxx

At the time of this writing, there have been no reports of Deramaxx toxicity in dogs.

If your dog has had too much Deramaxx and is suffering from toxicity, you may see some of the following signs:

  • A reduced appetite
  • Digestive side effects such as vomiting, diarrhea, dark colored feces
  • An increase in drinking and urination
  • Incoordination or seizures
  • Abnormal tiredness
  • Unusually heavy or fast breathing
  • Behavioral changes
  • Discomfort and pain in the abdomen

In any case where you suspect that your dog may have had an overdose of Deramaxx, it is important to call your veterinarian as soon as possible.

Toxicity can be fatal and acting fast will improve chances of recovery.

Take Home Message

Deramaxx is a popular anti-inflammatory for dogs that is often used to treat pain related to dog arthritis and joints or post-surgery.

There’s enough scientific evidence to conclude that Deramaxx is safe for dogs.

This NSAID has been proven to work in relieving pain for dogs as well as assisting with several other canine health conditions.

A few studies have shown some minor Deramaxx side effects such as vomiting and diarrhea.

[toggle title=”References“]

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